The writing on the wall

Zuzana Machackova, Czech Republic, Teacher: “I signed this because information on what was done and what was found in trials could be lost forever. It could lead to bad treatment decisions, missed opportunities for good medicine, and trials being repeated unnecessarily.”

Peter Huncar, Slovakia, IT: “I signed this because the more information is available the less space is there for rumors, myths, conspiracy theories etc.”

Sarah Twist, UK, Youth Worker: “I signed because lack of information regarding medication can cost lives”

Miroslav Martinoviӓ, Slovak Republic, self-employed software developer: “I signed this because until I saw this petition it never crossed my mind that all the clinical studies might not already be freely available. It seems utterly absurd that this is something that yet has to be done, and that it is something that has to be achieved through a petition…”

Robert Newcombe, UK, Professor of Biostatistics: “I signed because this issue is vital to the integrity and interpretability of our whole healthcare evidence base.”

Aidan Findlater, Canada Medical Student: “I signed this because I want to be confident that the treatments I will one day prescribe do more good than harm.”

Lucy Martin, UK, GP: “I believe I cannot make informed judgement or help patients make meaningful decisions about their own treatments without full access to all data on pharmaceutical products. This is a patient safety issue of the highest importance.”

Arana Homan, Australia, Medical Student: “I signed this because… not having access to all clinical trials data makes it too easy to publish biased results.”

Susan Bewley, UK, Professor of complex obstetrics: “I signed this because science becomes shaky without solid foundations and the elimination of bias. There is no justification whatsoever for conducting research on human subjects without a promise of using the results. Report everything – the positive, negative and even down-right peculiar. By applying the scientific principles of ‘many eyes’, we can make better and more rapid progress.”

Nicole Lacey, New Zealand: “I signed this because I let my child be registered on a clinical trial so that children in the future can have a better life with less side effects.  I expected that all results would be reported.”

Andrew Patterson, Canada, Software Developer: “I signed this because the whole point of clinical trials is to learn something useful. By not publishing, not only is that useful information being unethically hidden, it devalues existing data by introducing bias (good studies are published, bad are not). It is incalculably stupid that all trials are not published, and the harm that is causing is intolerable.”

Kate Mazurek, USA: “I signed this because while my mom underwent treatment for her stage two breast cancer she qualified for a clinical trial which she chose to participate in. She did so in hope that the results would aid and further us in treating cancer patients. Something about her results could benefit the future of cancer treatment. This is vital information that could only help us.”

Martin Rundkvist, Sweden, Archeologist: “I signed this because I find it fundamentally dishonest and scientifically counterproductive to withhold research results.”

Chris Shaw, UK, Retired: “I signed this because I want my doctor to have the best information available when he is prescribing drugs.”

Lee Shenton, USA, Retired: “I signed this because I have had cancer, two of my sisters have had cancer, many of my friends are fighting cancer, my father died of cancer.  I want to know that the therapies used have been properly tested and fully reported.  How else can any of us make a good decision about treatments?”

Anel Schoones, South Africa, Researcher: “I signed this because it is of utmost importance for health care decision-making, and trustworthiness of the health care profession.”

Richard Morris, Switzerland: “I signed this because, I have Leukaemia and I need the best knowledge to enable me to choose the best therapy. How can I or my doctor know what is best if research is not published?”

Wej Amo, Australia, Designer: “I signed this because I am surprised that they aren’t already”

Jeremy Taylor, UK, chief executive of National Voices: “I signed this because I am chief executive of National Voices, the coalition of health charities in England campaigning for a stronger patient voice in health. We care passionately about shared decision making and there can be no informed decisions without reliable and trustworthy information about treatments and therapies. Transparency is vital.”

Helena Bel Franquesa, Spain, medical student: “I signed this because clinical trials must be reported to keep improving medical treatments and to improve the work of doctors and researchers.”

Catherine Coughlan, France, lawyer: “I strongly believe that with out ALL the evidence neither scientists nor the general public are in a position to decide how effective treatments really are.”

Alex Borthwick, UK, software developer: “I signed this because I believe all evidence from clinical trials should be accurately recorded and made available to the scientific community, so that they can be appropriately scrutinised and decisions can be made based on all possible information.”

Shayne Power, Australia, pharmacist: “I signed this because Evidence Based Medicine would be so much better if we had ALL the evidence.”

Mirjana Huic, Croatia, clinical pharmacologist: “I signed this because our patients deserve it; there will be no Evidence-based medicine without all clinical trials data published transparently.”

Adrian Shergold: “I signed this because we need to know what doesn’t work, as well as what does work, if we are to improve treatments or develop new treatments and cures for the future.”

Sinead Fitzgerald, computer programmer: “I signed this because I believe in science and evidence and as full a picture as is possible. I also believe in trust – we need to be able to trust the decision makers and their sources.”

Joana Minga, Albania, student: “I signed this because information is very important for our future and information must be free.”

Gleb Volodin Russia, programmer: “I signed this because information is crucial in making important decisions, and it’s especially obvious in medicine. Specialists, who we trust to help us with our health problems, naturally have to be well-informed to make beneficiary decisions. And we have right to demand solid reassurance that our doctors basically know what they are doing when giving us a pill, or signing us for a treatment.”

Simon French, Australia, post-doctoral researcher: “I signed this because it is vital that healthcare professionals, policy makers and consumers have access to all necessary information to make informed choices.”

Bram van der Kolm, Netherlands: “Science should not just be about why it works but also about why it doesn’t.”

Ross McDowell, medical student: “I am a final year medical student studying in the UK. I had heard of publication bias many times over the course of my education but only recently came to understand its far reaching implications. I find that this problem exists when a solution is so simple absurd and indefensible. Admittedly administratively finding details of unpublished trials and ensuring that all trials are published presents a challenge, but when the steaks are so high it is a challenge that should surely be accepted.”

Gerard Crotty, Ireland, doctor: “I signed this because as a consultant haematologist I want the most reliable data available to inform us about what works and what doesn’t.”

Philip Reese, planning officer: “I signed this because as a patient I want to know what works.”

Katie Edwards: “I signed this because science cannot develop in isolation and secret.  And if patients truly have choice, then it should be informed choice, impossible if their doctors and experts themselves don’t have access accurate complete information.”

Glenda Sun, Canada, university science student: “I signed this because this is a very serious issue that needs to be resolved – it’s the responsibilities of the governments, academic institutions, drug industries, and the scientific communities to make sure that people who are using drugs or given drug prescriptions are making safe and informed decisions.”

Jens Bruin Ødegaard, Norway, engineering student: “I signed this because I am really angry that people are given harmful or unnecessary drugs because of something as simple as trials not being published.”

Sarah Dyer, GP: “I signed this petition because I want to know that the drugs I give to my patients actually work!”

Jennifer Durrant, NHS manager: “I signed this because the publication of results, good and bad, will prevent the replication of investment. Also, those participants who have been involved in a study should, as a matter of course, be informed of the results as stakeholders.  After all, their time and contribution ensure that research happens at all.”

Stephen Roberts, New Zealand, doctor (anaesthesia): “I signed this because after reading Dr Ben Goldacre’s latest offering Bad Pharma – I found myself incensed. How could I and so many others work in the field of healthcare – a supposedly ‘moral’ field of work and be peddling medications that often have sinister SE’s which we currently don’t know of despite there being buried evidence proving that industry did. Here’s to full and honest reporting of ALL trial data.”

Shea Wilson, Australia, GP: “I have signed this petition because I am outraged that I might be offering biased and incomplete medical advice. If we are to have any faith at all in evidence based medicine we must have acess to all the evidence.”

Steve Austin, clinical scientist: ”I signed this because truth is power and it is morally wrong to with hold inconvenient results.”

Marguerite Basilico, USA, medical student: “I signed this because as a future physician, it is of vital importance to me that I have access to all results of clinical trials – not just the favorable ones that drug companies choose to publish.”

Philip Dawid, professor of statistics: “I signed this because I care about collecting and using evidence in ways that are unbiased, informative, and not misleading.”

James Semple, pharmacist: “I signed this because the current situation stops me from properly doing my job.”

Myrto-Christina Athanassiou, Germany, journalist: “I signed this because I think all clinical studies should be published in order to avoid predictable mistakes in medicine!”

Peter Gøtzsche, Denmark, professor: “Selective reporting of clinical research results is scientific misconduct and a betrayal of patients’ trust, and it kills thousands of patients every year.”

Maria Cristina Turola, Italy, psychiatrist: ”I signed this because knowledge is freedom.”

Étienne Fortin-Pellerin, Canada, neonatologist: “I signed this because this is a matter of basic ethics”

Joel Longtine, USA, software engineer: “I signed this because, in my experience, opening up data provides insights that the original authors and collectors could never have seen, or certainly could not have seen easily or quickly. More eyeballs are better.”

Kusal Das, India, editor in chief: “I signed this because I believe it is an important issue for all the medical journal editors.”

Ranj Singh, GP: “I signed this because patients and professionals deserve open and honest information.”

Margaret Wilcox, patient advocate: “I signed this because if all trials – neg as well as positive – were fully published as soon as possible, it would result in patient benefit much earlier and prevent wasting time and resources of both researchers and patients.”

Drummond Rennie, USA, editor/ physician: “I signed this because I have been campaigning vigorously on this issue for over 20 years.”

Hilary Cass, GP: “I signed this because there is dangerous publication bias in favour of positive results.”

Richard Thomas: “I signed this because data transparency is a vital tool for research and for ensuring that treatments are effective safe and viable.”

Hamish Wright, New Zealand: “I signed this because we could be repeating harmful trials.”

David Lissauer: “I signed this because it is critical for patient safety that all trials conducted are published. As a researcher conducting clinical trials and systematic reviews I can see no reason that this should be allowed to continue.”

Katie McCombes: “I signed this because there is something deeply wrong with the world when medicine is hurting people because of something as easily fixable as this. Information is vital. We need all trial results for medicine to work at all.”

Alec Burslem: “I signed this because the exploitation of participants without adding to the sum of knowledge amounts to moral theft.”

Marc Wilson: “I signed this because I was trained as a scientist!  Data where you cherry-pick which results to use?  Worthless.”

Charles Beattie: “I signed this because I want to be prescribed drugs with the best information available.”

Paula de Matos: “I signed this because I work in bioinformatics and realise the importance of making all data publicly available to give all scientists the information they need to understand the biology and therefore design better drugs.”

Gerald Birch: “I signed this because I have been a holistic health practitioner for thirty years. Our work is based upon sound practice and unlike pharmaceutical drugs.”

Alan Samuel: “I signed this because… not doing it gives medicine & science a bad name.”

Tony Newman: “I signed this because I want my children and grandchildren to benefit from the best possible clinical care.  This will not become a reality unless all evidence from clinical trials is put in the public realm.”

Francois Venter, South Africa: “I signed this because I think it corrupts the entire knowledge enterprise to hide selected data.”

Kim Jefferson: “I signed this because I’m a pharmacist and it is difficult to make informed choices without an honest risk to benefit analysis.”

Jon Strayer, USA: “I signed this because… If you only have to report the studies with results you like then our understanding of the risks and benefits will be skewed.  You cannot give informed consent when negative results can be hidden.”

Paul Chaplin: “I signed this because as a potential patient, a taxpayer, and someone with an interest in the advance of medicine I believe the methods and results of all clinical trials (at the very least all paid for to any degree by public funds) should be recorded in an open manner to inform future decisions and ensure no information is lost.”

Max Loveridge: “I signed this because I would like any healthcare I consume in the future to be properly evidence based.”

Peter Burke: “I signed this because it is clear that the short term self interest of the few should not outweigh the welfare of humankind in general.”

Phill Coleman: “I signed this because knowledge is the way forward for us as a race.”

David Grabowski, Canada: “Every company whose business revolves around people’s health and safety should have the ethical and moral obligation to publish all trails performed on humans regardless of the outcome.”

Natalie Gould: “I signed this because I want to make sure that my Doctor has access to all the necessary information before prescribing me (and my neighbours) any medicines.”

Lynn Faulds Wood: “I signed this because I was diagnosed with advanced cancer when presenter of BBC Watchdog prog – I co-founded the European Cancer Patient Coalition and chaired it for 8 years – good information about drug performance & trials means life or death to many patients but we are frequently not getting it. It is appalling that pharma companies can choose how much to tell us & hide results they don’t like. Roche’s behaviour over Tamiflu is tantamount to fraud & the millions spent by the Uk gov & others returned. Patient organisations have often behaved disgracefully promoting drugs to the public which the companies are not permitted to promote – and not declared how much support they received – a murky business.”

Simon Cour-Palais: “I signed this because I abhor secrecy and because I believe that each of my parents (both doctors) would have signed it had they been alive.”

Michael Abbott: “I signed this because this is an abuse of the systems science developed to help us all.”

Casey Corrie, Australia: “I signed this because of the systematic bias that exists in failing to publish articles that show efficacy of therapy over medication. Also having worked on drug trials I have seen data twisted & methodology compromised to benefit drug company funding the research. More transparency & integrity is essential.”

Tamas Soroncz-Szabo, Hungary: “I signed this because unbiased evidence is essential for making health-care decisions. If the patient were your mother/child would you withhold the evidence?”

Alison Sneddon: “I signed this because… I am a doctor and believe in the importance of reliable unbiased evidence upon which to base clinical decision making.”

Jennie Hatherley, New Zealand: “I signed this because commonsense and integrity should prevail and the weight return to people coming before profit. As a person who needs drugs to survive and a person who just cares for all people making vital decisions about their future based on incomplete facts – I beseech governments to change the law and demand all trials past and present  to be registered and the full methods and results reported.  I mean why on earth not?  Every person who is prescribed a drug requires full knowledge of what they are taking.   This cannot continue. For what reasons are they hidden other than to protect a companies’ profit ahead of peoples’ lives. All should have the rights to not be guinea pigs for that is all we are if full information is not available.”

Elizabeth Scopacasa, Australia: “I signed this because… I want to make informed decisions with the CORRECT information particularly when it involves my children!”

Amy Barnston, Australia: “I signed this for the safety of myself, my baby, my family and friends. I believe that we should have the right to informed decisions (I thought it was illegal not to give people informed choices) on what we are taking and also giving to our children whom we are the voices for.”

Paul Ingraham, Canada: “As a health writer earnestly trying to respect the evidence, I have been amazed and dismayed for years by all the fixable glitches in the pursuit of knowledge,”such as the file-drawer effect.” I am thrilled by the prospect that even one of these problems might be solved by smart collective action.  Go AllTrials go!”

David Came, France: “I signed this because I have suffered the consequences of the secondary effects of drugs which were apparently known about but hidden from doctors and other health professionals.”

Ann Mowe: “I signed this because… I was on the Cosak trial last year and although I didn’t get the success I was hoping for it would be interesting to know how others got on.”

Pete Nicholls, New Zealand: “I signed this because I come from the open source software world where I get to benefit every day from the hard work and countless hours that other people have put into sharing their work with the world. I believe the scientific world can benefit every bit as much from the sharing of data as we get to and I find it deeply saddening to see the large breadth of scientific knowledge stuck in silos, behind paywalls, or omitted from history entirely. We can do better.”

Lawrence Hanney: “I signed this because I have two chronic diseases and firmly believe that what you don’t know CAN kill you, besides the traumatic effect on the medical team who sincerely want to do their best for you..”

Trisha Greenhalgh: “I signed this because… as a doctor I want to offer my patients the best treatments with a full and rigorous assessment of the chance of benefit and the risk of harm.”

Max Davie: “I signed this because as a clinician I am sick of only getting half of the story.”

Erin Halliday: “I am a member of the Northern Ireland Cancer Research Consumer Forum and support clinical trials.”

Michael Dean: “I signed this because as a patient and wish to know about development and up-to-date treatment, including trials, that may help me and my family both now and in the future.”

Martyn Frank: “I signed this because I work in the industry and feel the discovery of new medicines will be accelerated by full disclosure of clinical trials.”

Liam Kennedy, Ireland: “I signed this because… as a future doctor I want to have the very best evidence guiding my prescribing so that I know I’m choosing the best possible option for patients.”

Dr Prithwiraj Das: “I signed this because transparent research is better research.”

Allister Murphy, retired: “I signed this because I am a cancer patient who has benefited from a clinical trial. Without such trials we would not be seeing better treatments coming to market.”

Guy Fitzmaurice, barrister: “I signed this because… science should not be done in secret.”

Neil Young, programmer: “The more comprehensive the data the more effective the healthcare.”

Rich Stevens, USA, professor: “I signed this because… good medicine depends upon good science. If we only see positive statistically significant results we only see part of the story. As my professors told me you learn from an experiment whether the hypothesis was supported or not.”

Thomas Agombar, GP: “I signed this because knowing full clinical trial results will allow me to prescribe the best treatments for my patients.”

Richard Fuller, unemployed: “I signed this because… I have been suffering from MS for over 30 years and so am coming to the end of my life. I know little of medicine but it is vital that records are made and rules followed so if mistakes are made they can be seen and rectified.”

Richard Gatti, architect: “I signed this because in a previous life I was a scientist.”

David Wayne, consultant physician retired: “I signed this petition because it is vital for the proper practice of evidence-based medicine.”

Natalie Street, research scientist: “Following reading Ben Goldacre’s new book Bad Pharma I am fully aware of the importance in registering all clinical trials. Changes need to be made urgently.”

David Bright, USA: “I signed this because the best decisions will only occur when ALL scientific information and data is out in the open and available for review.”

Joseph Ross, USA, physician: “I signed this because I believe in open science.”

Colin Parker, Australia, emergency physician: “I signed this petition because it is unethical to conduct under-powered trials and worse to withhold results. Time to end the deception perpetrated by big pharma.”

Keith Barrington, physician: “I signed this because we all deserve the protection from ineffective or dangerous medical treatments that this would bring.”

Richard West, investigator: “I signed this because it is important as a patient to know what works and what does not work. Don’t just publish the good results – publish every trial to be transparent.”

Sue Cheshire, human givens therapist: “I signed this because I believe that medical treatments of all kinds should be truly evidence-based. This can only come about if trials are honestly and comprehensively reported and assessed.”

Anna Ray: “I signed this because I think it is important for us to make real informed decisions about the drug that we prescribe based on ALL the evidence.”

Elisabetta Santandrea, Italy, documentalist: “I signed this because… lost results are lost opportunities.”

Dulcie Lee: “I signed this because… science tells us the truth about the world and we need to tell the truth about science.”

Helen Franklin, decorator: “I signed this petition in support of my friends whose daughter is profoundly autistic and affected by this.”

Helen Wynne, IT problem manager: “I signed this because this information is too important to lose.”

Anne Crowe-Fortune, Ireland, community worker: “Because I care deeply about the issues involved. All trial results and reports of methodologies are essential to ensure science has the full and complete story. Lost or omitted trial results can leave outcomes open to misinterpretation and exploitation.”

Margaret Johnson, patient/carer representative: “I signed this because it is vitally important that all research is recorded with all results whether positive or negative.”

David Chuter, print manager: “I signed this because as a patient support group organiser and CPRG member I do see and know trial results do help in the awareness, treatment, patient quality of life/ care and does save and or extend life.”

Bob Drake: “It’s time for transparency. Let’s get those trials registered.”

Drew Burrett: “It is morally indefensible that vital information is denied to the medical profession in order to protect the interests of corporations whilst potentially endangering the lives of patients.”

Roger Henry: “Selective registration and reporting skews our interpretation and risks subverting statistical methods.”

Steven Pape: “Transparency on trials & results is the only way we can ensure that the public isn’t being deceived by commercial pseudo-science.”

Phil Booth: “As a patient and as a former clinical trial volunteer I am appalled that companies are allowed to put their own commercial interests in front of those who need medical help and those trying to give it. In a fair and open society all clinical trials should be registered and all results published – without exception.”

Samuel Edwards, Australia: “Modern medicine is a product of a worldwide scientific endeavour that can only flourish in a context of transparency.”

Jane Sullivan: “THIS is too important to ignore. All trials should be registered so that we know what results are missing. Negative results are as important as positive results.”

Chris Oates: “Currently waiting for GSK to decide whether I can publish my publicly funded work… The whole system needs overhauling. Release of historical trial data will be an important first step.”

Penelope Haccius, Switzerland: “Most people still think we live in a world where trial results are arrived at ‘scientifically’. This selection of the good stuff and hiding the bad or indifferent stuff under the carpet has never been science – just salesmanship. Shame on the perpetrators.”

Tim Sharpe: “This is essential for me to make informed decisions about my health and that of my family.”

Chris Cowsley: “Good information leads to good decisions. Withholding information is a way of manipulating the decision process. At best this is dangerously arrogant; sometimes it subjects others to unnecessary risk and/or expense. Even when it is ‘merely’ a selfish attempt to secure an unfair advantage withholding information is a reprehensible act from any party with a pretence to scientific credibility or social responsibility.”

Christopher Owen: “Obfuscation is the very opposite of science.”

Jim Byrne, Ireland: “To provide patients with evidence-based and effective treatment we need all the information. Publishing only one side of the story is no better than propaganda.”

Michelle Cain: “Not publishing clinical trial data for medicines/treatments is unethical — the worst kind of cherry-picking!”

Guy James: “This is the most important thing for the government to tackle in healthcare this decade. Let’s see it done.”

Cian McCafferty: “This is too important not to deal with now. Scientific progress could be significantly accelerated by the provision of all data to all researchers.”

Dave Cross: “This just seems like common sense to me. I was astonished to find that this isn’t already legally enforced.”

Matthew Jackson: “As a PhD student I am all too familiar with the culture of only seeing positive results published. The amount of hours of work that could be saved in a research laboratory if failed initial research material was published is staggering. It is even more shocking that research that contains the facts and details about potential harm to patients suffers the same fate.”

Peter Wise: “In 1986 the Government told me ‘Don’t die of ignorance.’ Now it is their turn to ensure that I don’t die of ignorance (or deliberately misleading advice).”

Rob Harris: “It is astounding that the NHS spends billions on drugs without having all the data showing exactly what they do. It’s just dangerous to withhold trials from doctors.”

Neale Swinnerton: “Businesses protect the bottom line by concealing failed projects. With medical trials failures are just as important for treatment decisions as successes. We must not let business practice dictate bad medical treatment.”

Nikos Askitas, Germany: “The collection of all frequencies in which you find no signal is an important piece of information. Researchers should be able to hunt for gold but it would be good if someone kept track of all the failed digs.”

Matt McKenzie: “We need a binding international law to ensure drug companies can make profits while benefiting the human race with accurate research paid for by these profits. Right now the profits are more important than the science and this approach leads to devaluing of scientific opinion and needless suffering.”

Tony Baines: “As a patient and parent I’m dismayed that the treatments that I and my family receive may have adverse outcomes that I cannot be told about. As a UK taxpayer I’m appalled that my money is being spent on expensive treatments that may not offer any improvement over cheaper alternatives.”

Karen Peterson, USA: “I signed this because I’m a scientist and I believe knowledge is power. What we don’t know can seriously hurt us.”

Stephen Parsons: “I signed this because I feel betrayed by my government and their affiliates in letting drug companies pursue their own wealth at the expense of our nation’s health by hiding/twisting relevant medical research and clinical trials”

Barry Stevens: “I signed this because people deserve to be treated with the best medicines available which provide the most positive results and not by the cheapest or the brand that provides the most convincing propaganda regarding its benefits.”

Mike Hoffman: “I signed this because… what you don’t know CAN hurt you.”

Kate Tuckey: “I have MS. I want to do my own homework on how to treat my condition. That involves gathering as much info as possible on all drugs/treatments etc. As an individual obviously I am unable to carry out such trials. The companies that carry out ANY trials have a public and moral responsibility to publish ANY results found for the good of humankind and for us to move forward as a civilisation by pooling knowledge.”

Marie Estcourt, Australia: “I signed this because as a scientist I believe that transparency is critical for clear scientific decision making as a patient and mother I want doctors to be able to make correct treatment decisions based on all evidence and finally as a person I feel that those who give their time and selves for trials deserve to see their efforts come to something not disappear into a void.”

Sarah Davidson: “I signed this because countless person-years of work have been wasted through replication of failed clinical trials. A spirit of openness among the academic and commercial clinical communities would be a boon to all and the public at the receiving end of treatment. Here’s to improving the efficiency of research through sharing.”

Julie Rouffiac: “I signed this because when I need to visit the doctor I want to feel confident she/he has the best information available when discussing treatment options.”

Alan Cassels, Canada: “I signed this because I believe not registering or reporting trials constitutes scientific misconduct and betrays the altruistic intentions of patients who volunteer to be subjects in trials.”

Carolyn Thomas, Canada: “I signed this because I’m a heart attack survivor who has no clue which of the fistful of meds I take each day has been prescribed for me based on flawed research or tainted journal articles.”

Ian Gallagher: “I signed this so that all of the data I collect from generous subjects will be used.”

Anjana Roy, USA: “I signed this because doctors at my hospital have asked for the results for trials with no luck. I feel results and progress of all trials should be made public.”

Amy Price: “It signed this because I have seen first hand and through the eyes of damaged patients and disillusioned medical professionals how important it is to have openness and transparency in clinical trials. Registering every trial is an important first step.”

Felix May: “Without full disclosure we’re singing from half a hymn sheet; science could be closer to the truth if only we all disclosed fully.”

Tammy Harman: “I signed this because I am living with the consequences of their non-disclosure.”

Andrew McLeod: “I signed this because… The positive bias from unpublished negative results mis-informs doctors and patients about the effectiveness and potential dangers of certified medicines while making profit for large pharmaceutical companies. The failure of regulating authorities to combat these occurrences necessitates measures such as this petition to raise awareness so that pressure may be exerted on such authorities to act in the interests of patients and the credibility of applied medical science.”

Helen Bedford: “I signed this because… my young son has a neuromuscular disease under research. He is dependent on drugs in order to function. I want / need to be able to access research trials and results – warts and all – in order to be able to properly assess treatment options and make the right decisions for him. In a world of ‘informed consent’ medical professionals push responsibility for undergoing treatment onto the patient (or parent) yet we are hamstrung – apart from not having years of training in specialist fields we do not have access to the research/trial results from which to attempt to make ‘informed’ decisions.”

Slavina Georgieva, Bulgaria: “I signed this petition because science builds on both the mistakes and successes of the past.”

William Vousden: “I signed this because I used to work in Biotech. It is too easy to bury bad news.”

Andrew France: “The lack of this accountability surely holds back advances in medicine.”

Emma McClure: “I signed this because concealed data costs lives.”

Tracey Johns, patient public involvement manager: “I signed this because I believe it is important for participants who willingly volunteer to give their time and commitment to researcher in order that other patients and the NHS may benefit from the knowledge generated. Also to improve evidence based decision making in health and transparency around this.”

June White, librarian: “I signed this because all evidence should be available to those whose practice must be based on the best evidence – affecting people’s health and lives.”

Joe Higman, social worker: “I signed this because we need all the information to make informed choices.”

Andy Hall, investor: “I signed this because… more light helps you see…”

Julie Miller, research facilitator: “I signed this because it is nice to give feedback to patients and GP’s that have signed to do the research.”

Will Parry, social researcher: “I signed this because without all the data there simply isn’t any evidence one way or the other!”

Helen Salisbury, GP: “I signed this because I need the most complete information possible to help my patients decide what treatments are right for them.”

Rachael Farnsworth: “I signed this on behalf of my infant daughter who is in a clinical trial at present.”

Sara Lands: “I signed this because the publication of trials could do so much to improve our knowledge and therefore the quality of treatments.”

Thomas Morris, radio producer: “I signed this because having read Ben Goldacre’s book on the subject I agree this is a serious issue that threatens to undermine sound medical practice.”

James Kennedy, engineer: “I signed this because it seems like a good idea and additional transparency is likely to save some lives at some point.”

Fabio Suzzi, Italy, GP: “I signed this because… all trials’ information and results (negative trials included) add useful knowledge to health professionals and to the general public.”

Phil Sanders, PhD student: “I signed this because I think that decisions should be based on evidence. When it comes to people’s health the patient should always be the priority and in a scientific discipline such as medicine evidence should be weighed without bias and decisions based on all the information possible.”

Lissa Herron, postdoctoral research fellow: “I signed this because the lack of transparency in clinical trials is harmful to patients.”

Louise Clement, primary care research facilitator: “I signed this because I believe there is much to be gained from the open access of scientific data.”

Simon Columbus, Netherlands, student: “Science needs transparency.”

Veronica Dudley, scientist: “I signed this because it is extremely important to have open access to all trial data.”

Patrizia Morelli, Italy, pharmacist: “Good medicine cannot allow the companies or researchers to withhold trial data even if negative. Patient’s health is a priority aver all the interests both commercial and scientific ones.”

Lynn Bruce, pharmacist: “I signed this because there is a risk not only of important positive research being lost but also of potential harm being hidden.”

Riccardo Fanciola, Switzerland, journalist: “I signed this because research is important.”

Chris Staddon, senior experimental officer: “I signed this because… I am an avid believer in the principles of scientific results to be free and fair and available to all.”

Chiara Pandolfini, Italy, epidemiologist: “It is fundamental for the advancement of scientific knowledge.”

Terri Oloughlin, Ireland: “I signed this because… it’s a waste of valuable resources and information to have repeats of the same research.”

Marina Grappa, Italy, lay member of ethics committee: “I signed this because it’s right physicians and patients know trials’ results. It’s absolutely right and necessary.”

Ailsa Donnelly, patient representative: “I signed this because science and the scientific method are meaningless unless they are absolutely open and transparent and above board.”

Simon Parker, CIO: “I signed this because I need to – I shouldn’t have to.”

Rebecca McDowall, treatment advocate: “I signed this because I think it’s ridiculous that we can’t access information about drugs that are being prescribed everyday!”

Gabriele Tucci, Italy: “I signed this because I’m a physician and I think that every part of research should be readily available.”

John King, psychologist: “Patients gave themselves honestly to these trials in the expectation of contributing to the advancement of medical knowledge. The advancement of Pharma profit is not the same thing.”

Nicola Hart, Ireland, speech and language therapist: “I signed this because evidence based practice is essential.”

Olga Polikina, Russia, medical doctor: “I signed this because as a doctor I want a full disclosure of trials results to benefit both medical and patients communities.”