Latest Campaign Updates

Companies ranked by drug trial transparency

A new study published in BMJ Open found that for 15 drugs approved by the US Food and Drug Administration (FDA) in 2012, a median 57% of clinical trials were registered, and only 65% of trial results were publicly available. Almost half of the drugs had at least one undisclosed phase II or III trial. […]

17th November 2015|

Could UK research ethics regulator monitor publication bias?

Research published in BMC Medical Ethics  has found that NHS research ethics committees (RECs) could monitor bias in clinical trial publication and outcome reporting. RECs review all applications for NHS research conducted in the UK and determine whether the research is ethical. There are currently more than 60 RECs across the UK that each year review […]

4th November 2015|

Trends in global clinical trial registration

The number of clinical trials registered globally increased from 3,294 in 2004, to 23,384 in 2013, according to new research published in BMJ Open. The study looked at clinical trials on the World Health Organisation’s International Clinical Trials Registry Platform (ICTRP), which contains data from 16 global trial registries. The research analysed global progress in […]

2nd November 2015|

How much transparency does Canada’s new law allow?

This blog was originally published on The BMJ blogs site at
Diclectin Data: Testing Canada’s New Pharmaceutical Transparency Law
Matthew Herder a & Trudo Lemmens b
Earlier this month Canadian news sources, including the CBC and the Toronto Star, reported on Dr. Navindra Persaud’s success in securing unpublished data from Health Canada about the safety and effectiveness […]

28th October 2015|

Clinical trial publishing game, from The Economist

The results of around half of all clinical trials have never been published. Failing to publish results means the people who make decisions about medicines don’t have full information about the benefits and risks of treatments we use every day.

Use The Economist’s publication bias simulator to run clinical trials yourself, decide which trials to publish, and see how much […]

6th October 2015|

Cipher machine used to hide secrets will be auctioned to help reveal medical secrets

We are delighted that Simon Singh, science writer and Sense About Science trustee, is auctioning his Second World War cipher machine to raise money for the AllTrials campaign and Good Thinking.

The M-209 is a portable mechanical cipher machine (about the size of a lunchbox) that was used by the US military during WW2 and the […]

1st October 2015|

Plastic Surgeons join AllTrials and call on next generation of surgeons to support the campaign

The British Association of Plastic, Reconstructive and Aesthetic Surgeons (BAPRAS) has joined AllTrials and is calling on the next generation of surgeons to support the campaign.  BAPRAS and the Reconstructive Surgery Trials Network (RSTN) have committed to register all trials they’re involved with and will report results within one year of trial completion. BAPRAS has also […]

18th September 2015|

New research on old data

Many supporters of AllTrials will be interested in a study published in The BMJ today, a reanalysis of previously hidden clinical trial data. The new research used data from a 1990s clinical trial of the GlaxoSmithKline (GSK) antidepressant drug paroxetine. Today’s findings contradict a 14-year-old analysis of the data referred to as Study 329, which found paroxetine to be safe and […]

17th September 2015|

UK autism research charity make strong commitment to trials transparency

Autistica, a UK charity that has raised over £8.5 million in support of autism research has pledged its support for trials transparency by joining AllTrials and adopting the principles of the campaign as part of its grant awards process.

On joining the campaign, Autistica said:
“Autistica is a vital bridge between a diverse autism community and medical […]

10th September 2015|

WHO calls for data sharing “by default” in public health emergencies

The World Health Organization (WHO) has said that clinical and epidemiologic data should be made openly available, as close to real-time as possible, during public health emergencies.

In Geneva yesterday, representatives from Government, public health agencies, scientists, research funders, ethicists and industry met to discuss data sharing in light of the recent Ebola crisis. Participants agreed […]

3rd September 2015|