Latest Campaign Updates

Patients’ and doctors’ campaign welcomes plans to tackle unjust and dangerous problem of hidden clinical trials

The AllTrials campaign, which has been calling for all clinical trials past and present to be registered, and full methods and results made available, today welcomed new proposals by the US Department of Health and Human Services (HHS) and National Institutes of Health (NIH) to expand reporting of clinical trial results, and to make that […]

20th November 2014|

EU Ombudsman asks medicines regulator why trial information is being kept hidden

The European Ombudsman, Emily O’Reilly, has asked the European Medicines Agency (EMA) why it agreed to keep large amounts of information hidden about clinical trials on the medicine Humira. AbbVie, the manufacturer of Humira, had sued the EMA to keep the information confidential. As part of a settlement announced in April, the EMA agreed to […]

12th November 2014|

Individual patient data showed chemotherapy leads to better brain tumour survival rates

A review of the individual patient data from 12 clinical trials showed that chemotherapy provided a small but significant increase in survival among people with the most common type of brain tumour.

Malignant gliomas are a deadly cancer of the brain and spine, most common in childhood and at age 50-60 years. Treatment generally involves […]

12th November 2014|

Using individual patient data to find the best surgery for hernias

Following an analysis of individual patient data (IPD), doctors were able to offer a less painful surgery to treat the most common type of hernia.

When people age, muscles become weaker and the intestines can sometimes push through weak spots causing a hernia. These can be painful and in some cases require surgery to treat. […]

11th November 2014|

A series on the value of individual patient data sharing

To lay bare the benefits and harms about medicines, researchers often need to get into the nitty-gritty details found in the data from the participants in clinical trials. Summary results often just don’t cut it. This week, AllTrials will be highlighting some of the research that demonstrates the benefits of these detailed analyses to […]

10th November 2014|

Strong transparency proposals from US clinical trial funder

Clinical trials funded by a large US funder will have to be registered before they begin and their results made available within one year of completion under its proposed policy. The Patient Centered Outcomes Research Institute (PCORI) is currently deciding how it will make the findings from research that it funds public. Since it […]

7th November 2014|

New EMA policy could “revolutionise publishing”

In a new post on PLOS Blogs, Tom Jefferson looks at what Europe’s medicines body’s new policy on releasing information from clinical trials might mean for journals and researchers who combine clinical trial information in systematic reviews. This is the policy that that hundreds of you wrote to the European Medicines Agency about. Jefferson, who […]

4th November 2014|

Society of Biology joins AllTrials

The Society of Biology, a UK learned society for academics, industry, and researchers in biology, has just joined AllTrials. This is fantastic, the Society represents 90 organisation and 14,000 individual members.

Here is the Society of Biology’s statement:
The Society of Biology is pleased to announce its support for aims of the AllTrials petition. The Society […]

24th October 2014|

You can help shape a new global statement on clinical trial reporting

We have a chance to get the most influential health body in the world – the World Health Organisation (WHO) – to say something strong on the need for the results of all clinical trials to be publicly reported. Following all of our pressure, the WHO has decided it needs to say something about […]

23rd October 2014|

Read moving comments in support of clinical trial transparency

The UK’s Health Research Authority (HRA) has published the feedback it received to its clinical trial transparency proposals. Look at pages 6-13 for some of the most compelling and moving reasons for clinical trial transparency that we’ve seen.

Hundreds of you wrote to the HRA in July to support its proposals. Thanks to your support, […]

21st October 2014|