Latest Campaign Updates

Ongoing judicial review against the Health Research Authority

Richmond Pharmacology has launched a judicial review against the Health Research Authority over its work to further clinical trial transparency. The AllTrials campaign has decided to intervene. This is extraordinarily time-consuming and your donations help make sure we can keep the AllTrials campaign moving while the court case is going on.

Here you’ll find updates to this ongoing […]

26th June 2015|

Half of trials on high-risk cardiovascular devices remain unpublished

Only one in two clinical trials on high-risk medical devices for heart disease are published in a peer-reviewed journal, according to a new study published in The BMJ. These devices include implantable cardioverter-defibrillators, pacemakers, coronary stents, and artificial heart valves. Researchers searched an FDA database and found information about 177 clinical trials on 106 cardiovascular devices that received […]

24th June 2015|

Head-to-head clinical trials “almost always” back industry sponsor

A new study published in the Journal of Clinical Epidemiology has found that industry-sponsored clinical trials comparing different treatments “systematically yield favourable results for the sponsors.” Researchers looked at 319 trials with over 100 participants published in academic journals in 2011. Of the 182 trials funded by pharmaceutical companies 83% had positive results compared to […]

19th June 2015|

Chief Medical Officer calls for medicines review to restore public trust

Professor Dame Sally Davies, the Chief Medical Officer for England and the most senior health advisor in government, has called for an independent review of the safety and efficacy of medicines.

The review, which started on 17th June, is being conducted by the Academy of Medical Sciences (AMS) and will explore how different sources of evidence […]

18th June 2015|

UK Government cites AllTrials in G7 transparency pledge

The Department of Health has told us more detail behind UK Prime Minister David Cameron’s comments at G7, on the need for trials transparency in public health emergencies.

The new commitment is that whenever a UK Government body funds or co-funds research or work into diseases that are a threat to global health security, that work will […]

11th June 2015|

Prime Minister calls for G7 agreement on clinical trial transparency

To combat the outbreak and spread of deadly viruses like Ebola, UK Prime Minister David Cameron is urging G7 leaders to develop an international agreement to require all clinical trials to be published. The recent Ebola outbreak showed that when data on disease outbreaks is not shared quickly, the disease can get out of control. […]

8th June 2015|

Imiquimod story highlights the danger of hidden trials

A commentary published in JAMA Dermatology has highlighted yet another extraordinary case of unpublished trials.

It looks at the case of imiquimod, widely considered beneficial for treating children with molluscum contagiosum (a viral infection that affects the skin). In fact, 2 large randomised clinical trials have shown imiquimod is neither safe nor effective in these cases.1,2

These […]

5th June 2015|

Europe’s Clinical Research Infrastructures Network joins AllTrials

The European Clinical Research Infrastructures Network (ECRIN) has joined AllTrials, saying “ECRIN promotes transparency in clinical trials, including commitment to publish and commitment to provide access to patient-level data.” ECRIN is a not-for-profit organisation that provides hands-on support and tools for multinational clinical research projects in Europe.

Dr Trish Groves, deputy editor and editor-in-chief, BMJ Open […]

2nd June 2015|

New guidance on data sharing published

New guidelines for how to share data from publicly funded clinical trials have gained the support of the UK Government’s health research funding body, the National Institute for Health Research (NIHR).

Data sharing makes clinical trials more useful to researchers. The contribution made by clinical trial participants can be put to greater use and unnecessary duplicate […]

28th May 2015|

Pharma company makes some trial data available: step in the right direction

Eisai Co., Ltd, a Japanese pharmaceutical company, has announced it is making some of its clinical trial data available to researchers through the external website www.clinicalstudydatarequest.com.

Eisai has said it will share clinical trial data only from trials of products approved after 1st January 2014, in Europe and the United States. This is the level of transparency that guidelines from industry bodies EFPIA and PhRMA recommend. Now, […]

28th May 2015|