Latest Campaign Updates

Systematic review makes good use of unpublished trial data

A systematic review on beta-blockers for high blood pressure has for the first time used data from two large clinical trials that were previously unavailable. The review from the Cochrane Collaboration analysed data from eight clinical trials that included nearly 1500 patients who had been treated with either carvedilol or labetalol. The two largest trials […]

27th August 2015|

AllTrials and EMIG open letter to the HRA – Reply

Last week, AllTrials and the Ethical Medicines Industry Group wrote to the Health Research Authority (HRA), to let them know that AllTrials supporters, the UK biopharmaceutical industry, and the English Courts support their continued work on clinical trials transparency.  Today, the HRA published a responding letter from Dr Janet Wisely, CEO of the HRA, alongside a statement in relation […]

25th August 2015|

Registration not being enforced by psychiatry journals

A new study in PLOS ONE found that, despite International Committee of Medical Journal Editors (ICMJE) guidelines, only one third of clinical trials published in the five most influential psychiatry journals were correctly registered before patient enrolment. In 2005, the ICMJE introduced the prospective registration guidelines, which led to many journals making prospective registration a condition for publication.

Looking at […]

21st August 2015|

Half of all clinical trials have never reported results

We’re sometimes asked if it’s still true that around half of clinical trials have never reported results. Yes, it is.

Some people point towards recent studies that found a higher rate of publication than that. Great! With all the campaigning, new laws, new regulations and emerging codes of conduct we and others have worked towards, it comes […]

20th August 2015|

AllTrials and EMIG open letter to the HRA

In the recent judicial review against the Health Research Authority (HRA), the UK’s ethical approval body for clinical trials, a clinical trials company tried to challenge the HRA’s attempts to monitor whether applicants are registering all their trials. Despite the Court’s judgment – that the HRA has a clear legal right to monitor researchers’ compliance with all their legal and ethical obligations – we cannot ignore the […]

19th August 2015|

Royal College of Surgeons joins AllTrials

The Royal College of Surgeons of England (RCS), a professional membership organisation and registered charity representing over 20,000 surgeons internationally has joined AllTrials.

On joining the campaign, the RCS, which exists to advance surgical standards and improve patient care, are keen to stress the urgency with which the community must improve clinical trial transparency around non-regulated interventions (treatments other than drugs and […]

17th August 2015|

NICE to allow companies to hide information? Our response

We’ve just learnt that NICE is suggesting that it allows medical technology companies to submit information from clinical trials to the development of NICE’s guidelines, without demanding those companies are complete and transparent about the trial information they have.

National Institute for Healthcare and Excellence (NICE), the UK body that draws up guidelines for the NHS, […]

6th August 2015|

Note from Ben Goldacre on 2 awesome weeks for AllTrials

Hi all,

I’ve wrestled the keyboard away from the AllTrials staff to send this email because, after two years of work – from tiny beginnings – with your help, the campaign has had a ridiculously good two weeks. It’s a cliché, so revoke my writing license, but this is all down to you and to your […]

6th August 2015|

The story of AllTrials

In May 2015, Trevor Butterworth, Director of Sense About Science USA, interviewed Ben Goldacre and Síle Lane to talk about the history of the AllTrials campaign.   


Almost half of all the clinical trials ever conducted have never been reported.
This is the story of the campaign to find them—and to fix medicine.
“I felt like I was […]

31st July 2015|

AllTrials US campaign officially launched

We are delighted to announce that today AllTrials USA has officially launched. Today 50 patient support groups, medical societies, universities and consumer groups are coming together to launch the AllTrials campaign in the US and to say:
“We are calling on everyone in our sector to join us in supporting the AllTrials campaign. Hundreds of thousands […]

29th July 2015|