Our review of the world’s largest pharmaceutical companies’ trial registration and reporting policies is now published in the BMJ. This is the first time anyone has systematically examined and compared published company policies on trial transparency.
We found:
Most of the largest companies, though not all, have some sort of publicly stated policy about registering and reporting results from current […]
Some of the world’s largest research funders and NGOs today agreed to adopt the WHO’s strong standards on clinical trial transparency. This means all clinical trials they fund or support will be registered and the results reported.
In a joint statement, nine major funders including Médecins Sans Frontières, the Bill & Melinda Gates Foundation, the Indian Council of Medical […]
Canadians: now is our best chance to get Health Canada to take a big step towards making results from all clinical trials available.
Back in 2014, the Canadian government passed the Protecting Canadians from Unsafe Drugs Act, commonly known as Vanessa’s Law. Following pressure from AllTrials, the law gave the Minister of Health the authority to […]
The latest issue of the Advanced Emergency Nursing Journal includes an editorial on the importance of clinical trial transparency.
Evidence-based practice has become an expectation in health care. In recent years, the retraction of studies based on scientific fraud and outright fabrication of data has been highly publicized in both popular and scientific literature. Although the […]
AARP (formally the American Association of Retired Persons) joins AllTrials. With close to 38 million members, this is a fantastic addition to the global call for clinical trial transparency.
AARP recognizes the importance of clinical trial transparency and supports the AllTrials campaign, which calls for the registration of all clinical trials and the publication of their […]
In early October 2016, JAMA Internal Medicine published a paper indicating that less than half of failed Phase III clinical trials are subsequently published in peer-reviewed journals. The authors warned that the widespread failure to publish such failed trials hinders medical progress, wastes resources, and places patients in harm’s way.
The paper examined the development process […]
A systematic review published in September 2016 indicted that adverse events reporting in academic journals may be improving. The review, which examined 368 journal articles about clinical trials that tested spinal manipulative therapy interventions, found that only 38% of all articles reported on adverse events, but that the rate among articles published since 2010 was […]
A study published in September 2016 found major discrepancies in the reporting of clinical trials involving children. A team of researchers examined 20 trials and discovered that “all 20 trials selectively reported or failed to report main outcomes”.
In addition, the researchers found:
13 trials completed early without justification
11 downgraded or modified primary outcome or upgraded secondary […]
New automated clinical trials tracker shows around half of all trials have not published results, shines a spotlight on the worst companies and universities.
Nearly half of trials run by major trial sponsors in the last decade are missing results according to a new automated clinical trials tracker launched today. The TrialsTracker* identifies trials on the […]
Today, the European Medicines Agency for the first time ever proactively releases key documents that will allow independent researchers to verify pharmaceutical companies’ claims about the safety and effectiveness of new medicines. Clinical Study Reports, as the documents are called, provide detailed information on the methodologies and results of clinical trials. Today’s release represents a […]