Royal College of Paediatrics and Child Health: Over the last few years public confidence in some of our great institutions has been damaged by a series of scandals and cover-ups and this has created an even more profound obligation on all of us working in the healthcare sector to be as transparent and open about the work we do.  The pharmaceutical industry has and will continue to have a central role in developing effective products for licence as medicines but to maintain the trust of the public it has to do so on the basis of full publication of research trials so that any decisions to licence or use them can be made fully informed of all the evidence.